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CD152 (CTLA-4) Armenian Hamster anti-Mouse, Biotin, Clone: UC10-4B9, eBioscience™

Armenian Hamster Monoclonal Antibody

Marke:  Affymetrix eBioscience 13-1522-82

Additional Details : Gewicht : 0.25000kg

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Artikelnummer. 15269739

  • 149.00 CHF / 100 Mikrogramm


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Beschreibung

Beschreibung

It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Furthermore, due to the intracellular localization of a large portion of CTLA-4, for complete detection it may be necessary to assess intracellular expression, in addition to surface expression of CTLA-4. Filtration: 0.2 μm post-manufacturing filtered. CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
Spezifikation

Spezifikation

CD152 (CTLA-4)
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P09793
CELIAC3, CTLA-4, GRD4, GSE, ICOS, IDDM12, CD152 isoform, celiac disease 3, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte antigen 4
Armenian Hamster
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
UC10-4B9
Biotin
Ctla4
Liquid
Ctla4
IgG
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
12477
Videos
Dokumentation

For Research Use Only.