missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CD127 Monoclonal Antibody (eBioRDR5), Super Bright™ 436, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
195.00 CHF - 448.00 CHF
Spezifikation
| Antigen | CD127 |
|---|---|
| Klon | eBioRDR5 |
| Konzentration | 5 μL/Test |
| Anwendungen | Flow Cytometry |
| Klassifikation | Monoclonal |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15825513
|
Affymetrix eBioscience
62-1278-42 |
100 Tests |
448.00 CHF
100 Stück |
Verfügbar ab: 10-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
|||||
|
15815513
|
Affymetrix eBioscience
62-1278-41 |
25 Tests |
Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11. |
||||||
Beschreibung
Description: The eBioRDR5 monoclonal antibody reacts with human CD127 (Interleukin-7 Receptor alpha). CD127 complexes with CD132, also known as the common gamma chain (gamma c), to form the multi-functional IL-7 receptor (IL-7R). CD127 is a type I glycoprotein with a molecular weight of 75-80 kDa and is expressed by immature B cells through the early pre-B stage, by thymocytes during several stages of their development, and on most mature T cells, with transient down-regulation upon activation. Binding of IL-7 results in signal transduction which occurs through several tyrosine kinase pathways including the Jak/STAT pathway. IL-7 is indispensible for the development of lymphocytes, and the control of homeostatic proliferation of T-cells in the periphery. In addition, IL-7R signaling is know to be involved in the regulation of T cell receptor (TCR) locus rearrangement in gamma delta T cells. Interestingly, recently it has been demonstrated that CD127 expression is down-regulated on CD4+CD25+ regulatory T cells (T regs). While the co-expression of CD4 and CD25 has become widely used as an indicator of T regs, this method of identification may also include cells without suppressive activity.
CD127 Monoclonal antibody specifically detects CD127 in Human samples. It is validated for Flow Cytometry.Spezifikation
| CD127 | |
| 5 μL/Test | |
| Monoclonal | |
| Liquid | |
| RUO | |
| P16871 | |
| IgG1 κ | |
| Affinity chromatography | |
| Antibody |
| eBioRDR5 | |
| Flow Cytometry | |
| Super Bright 436 | |
| Mouse | |
| Human | |
| 3575 | |
| Primary | |
| 4° C, store in dark, DO NOT FREEZE! |
For Research Use Only