CD107b (LAMP-2) Mouse anti-Human, Clone: eBioH4B4 (H4B4), eBioscience™
Mouse Monoclonal Antibody
Marke: Affymetrix eBioscience 14-1078-80
Additional Details : Gewicht : 0.01000kg
BeschreibungPurity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Lysosomes are membrane-bound vacuoles which play a critical role in cellular metabolism. These organelles participate in endocytosis, the synthesis and assembly of acid hydrolases, act as sites for digestion of foreign materials and for specialized autolytic cellular processes. Membrane-associated glycoproteins have an important role in normal lysosomal function. Prior to posttranslational modification, Lysosome Associated Membrane Protein 2 (LAMP 2) is an ∽45 kDa polypeptide. Mature, functional LAMP 2 is extensively glycosylated with a variety of different N-linked and O-linked oligosaccharides with a total molecular weight of ∽100-110 kDa. LAMP 2 has a structure comprised of a large amino-terminal intra-lysosomal domain, a hydrophobic trans-membrane domain, and a short carboxyl-terminal cytoplasmic tail.
|PBS with 0.09% sodium azide; pH 7.2|
|RP23-193O17.2, CD107b, Lamp-2, Lamp-2a, Lamp-2b, Lamp-2c, Mac3|
|Flow Cytometry, Western Blot|
For Research Use Only.