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Invitrogen™ c-Met Biosimilar Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody
447.00 CHF - 1128.00 CHF
Spezifikation
| Antigen | c-Met Biosimilar |
|---|---|
| Konzentration | 1 mg/mL |
| Inhalt und Lagerung | -20°C, Avoid Freeze/Thaw Cycles |
| Anwendungen | ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance |
| Klassifikation | Recombinant Monoclonal |
| Product Code | Brand | Menge | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Menge | Price | Quantity & Availability | |||||
30284083
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Invitrogen™
MA559483 |
100 μg |
447.00 CHF
100 Mikrogramm |
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|
30284371
|
Invitrogen™
MA559484 |
1 mg |
1128.00 CHF
1 Milligramm |
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Description
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °. This antibody can also be cross referenced by the term SAIT301.
MET (cMET) is a receptor-like tyrosine kinase whose dysregulation has been linked to many types of human malignancies. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC. MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation. It also plays a role in adults including wound healing, organ regeneration, and tissue remodeling. MET has been linked to cancers including gastric, renal, and breast; therefore, making it a target for cancer therapeutics and diagnostic testing.Specifications
| c-Met Biosimilar | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Recombinant Monoclonal | |
| Lyophilized | |
| IgG1 | |
| Human | |
| Primary | |
| Protein A |
| 1 mg/mL | |
| ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance | |
| Unconjugated | |
| Human | |
| RUO | |
| 25mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2 | |
| Antibody |
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