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BRCA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 19791-1-AP-20UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16839274

  • 131.19 CHF / 20 Mikroliter

Verfügbar ab: 28-06-2022
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Beschreibung

Beschreibung

Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintece of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.
Spezifikation

Spezifikation

BRCA2
Polyclonal
Unconjugated
BRCA2
BRCA2, BRCC2, breast cancer 2, early onset, BROVCA2, FACD, FAD, FAD1, FANCB, FANCD, FANCD1
Rabbit
Antigen Affinity Chromatography
RUO
12190, 360254, 675
Antibody
IgG
Immunohistochemistry (Paraffin), Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O35923, P51587, P97929
Brca2
Peptide
20 μL
Primary
Mouse, Human, Rat
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote