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ACROBiosystems Biotinylated Human TIGIT Protein, Fc,Avitag™

MALS verified

437.70 CHF - 1925.89 CHF

Spezifikation

Zugriffsnummer NP_776160.2
Molekulargewicht 41.3 kDa
Quelle Biotinylated Human TIGIT, Fc,Avitag (MALS verified) (TIT-H82F1) is expressed from human 293 cells (HEK293). It contains AA Met 22 - Pro 141 (Accession # Q495A1-1).
Immunogen Met 22 - Pro 141
Lagerungsbedingungen -20°C
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15837787
Unterlagen ansehen Aktionsdetails
ACROBiosystems
TIT-H82F1-25UG
25 μg
437.70 CHF
25 Mikrogramm
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Verfügbar ab: 10-04-2024
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15827787
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ACROBiosystems
TIT-H82F1-200UG
200 μg
1925.89 CHF
200 Mikrogramm
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Sparen Sie bis zu 
»
Verfügbar ab: 10-04-2024
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Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is also known as V-set and immunoglobulin domain-containing protein 9 (VSIG9), V-set and transmembrane domain-containing protein 3 (VSTM3),which belongs to single-pass type I membrane protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level). TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 41.3 kDa. As a result of glycosylation, the protein migrates as 45-55 kDa under reducing (R) condition, and 85-115 kDa under no
Spezifikation

Spezifikation

NP_776160.2
Biotinylated Human TIGIT, Fc,Avitag (MALS verified) (TIT-H82F1) is expressed from human 293 cells (HEK293). It contains AA Met 22 - Pro 141 (Accession # Q495A1-1).
-20°C
TIGIT
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
MABSol™ Biotin Labeled Proteins
41.3 kDa
Met 22 - Pro 141
TIGIT,VSIG9,VSTM3
Precision Avi
Fc Tag and Avi Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by SDS-PAGE
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Product Certifications