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ACROBiosystems Biotinylated Human TIGIT Protein, Avitag™,His Tag

Recommended for biopanning

Marke:  ACROBiosystems TIT-H82E5-25UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15817787

  • 403.01 CHF / 25 Mikrogramm


Verfügbar ab
28-05-2021
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is also known as V-set and immunoglobulin domain-containing protein 9 (VSIG9), V-set and transmembrane domain-containing protein 3 (VSTM3),which belongs to single-pass type I membrane protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level). TIGIT binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 16.8 kDa. The protein migrates as 18-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

AAI01290
HEK293
Human
16.8 kDa
25 µg
Met 22 - Pro 141
TIGIT,VSIG9,VSTM3
Precision Avi
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>95% as determined by SDS-PAGE
Biotinylated Human TIGIT, Avitag,His Tag (recommended for biopanning) (TIT-H82E5) is expressed from human 293 cells (HEK293). It contains AA Met 22 - Pro 141 (Accession # Q495A1-1).
-20°C
TIGIT
His Tag and Avi Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation