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ACROBiosystems Biotinylated Human PD-L2 / B7-DC Protein, Fc, Avitag™
Biotinylated Protein
Marke: ACROBiosystems PD2-H82F6-200UG
Additional Details : Gewicht : 0.00001kg
Beschreibung
Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 51.0 kDa. The protein migrates as 66-91 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Spezifikation
AAI13679 | |
200 μg | |
Leu 20 - Pro 219 | |
PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2 | |
Precision Avi | |
Fc Tag and Avi Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by reduced SDS-PAGE |
51.0 kDa | |
Biotinylated Human PD-L2, Fc,Avitag (PD2-H82F6) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 219 (Accession # Q9BQ51-1). | |
-20°C | |
PD-L2 | |
Human | |
Tris with Glycine, Arginine and NaCl, pH7.5 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |