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ACROBiosystems Biotinylated Human PD-L2 / B7-DC Protein, Fc, Avitag™

Biotinylated Protein

Marke:  ACROBiosystems PD2-H82F6-25UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15827517

  • 441.35 CHF / 25 Mikrogramm
Verfügbar ab: 02-05-2024
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Beschreibung

Beschreibung

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 51.0 kDa. The protein migrates as 66-91 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

AAI13679
25 μg
Leu 20 - Pro 219
PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2
Precision Avi
Fc Tag and Avi Tag
Less than 1.0 EU / μg by the LAL method.
Powder
>95% as determined by reduced SDS-PAGE
51.0 kDa
Biotinylated Human PD-L2, Fc,Avitag (PD2-H82F6) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 219 (Accession # Q9BQ51-1).
-20°C
PD-L2
Human
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
MABSol™ Biotin Labeled Proteins
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote