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ACROBiosystems Biotinylated Human PD-L1 / B7-H1 Protein, Avitag™,His Tag (recommended for biopanning, MALS verigied)

Biotinylated Protein

Marke:  ACROBiosystems PD1-H82E5-25UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15827477

  • 443.32 CHF / 25 Mikrogramm


Verfügbar ab
26-05-2021
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Beschreibung

Beschreibung

Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 27.8 kDa. The protein migrates as 33-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_054862.1
HEK293
Human
27.8 kDa
25 µg
Phe 19 - Arg 238
PD-L1,CD274,B7-H1,PDCD1L1,PDCD1LG1
Precision Avi
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>95% as determined by SDS-PAGE
Biotinylated Human PD-L1, Avitag™,His Tag (recommended for biopanning) (PD1-H82E5) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Arg 238 (Accession # NP_054862.1).
-20°C
PD-L1
His Tag and Avi Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation