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ACROBiosystems Biotinylated Human IL-7 R alpha / CD127 Protein, Fc, Avitag™
Biotinylated Protein
Marke: ACROBiosystems IL7-H82F8-200UG
Additional Details : Gewicht : 0.00001kg
Beschreibung
Interleukin-7 receptor subunit alpha (IL-7 RA or IL7Ra) is also known as cluster of differentiation 127 (CD127). IL-7 RA is a type I cytokine receptor and is a subunit of the functional Interleukin-7 receptor and thymic stromal lymphopoietin (TSLP) receptors. IL-7 RA has been shown to play a critical role in the development of immune cells called lymphocytes - specifically in a process known as V(D)J recombination[citation needed]. This protein is also found to control the accessibility of a region of the genome that contains the T-cell receptor gamma gene, by STAT5 and histone acetylation.
This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 53.3 kDa. As a result of glycosylation, the protein migrates as 70-100 kDa under reducing (R) condition, and 130-200 kDa underSpezifikation
| 53.3 kDa | |
| Biotinylated Human IL-7 R alpha, Fc,Avitag (IL7-H82F8) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Gly 236 (Accession # P16871-1). | |
| -20°C | |
| IL-7 R alpha | |
| Human | |
| Tris with Glycine, Arginine and NaCl, pH7.5 | |
| HEK293 | |
| MABSol™ Biotin Labeled Proteins |
| 200 μg | |
| Glu 21 - Gly 236 | |
| IL7Ra,CD127 | |
| Precision Avi | |
| Fc Tag and Avi Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |