Learn More
ACROBiosystems Biotinylated Human FcRn / FCGRT&B2M Heterodimer Protein, Avitag™,His Tag&Strep II Tag (SPR & BLI verified)
Biotinylated Protein
Marke: ACROBiosystems FCM-H82W4-200UG
Additional Details : Gewicht : 0.00001kg
Beschreibung
FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Biotinylated Human FCGRT&B2M Heterodimer Protein, Avitag,His Tag&Strep II Tag (SPR & BLI verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 34.1 kDa (FCGRT) and 13.1 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag atSpezifikation
NP_004098.1 (FCGRT) and NP_004039.1 (B2M) | |
200 μg | |
Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M) | |
FcRn,FCGRT and B2M | |
Precision Avi | |
His Tag and Strep Tag and Avi Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |
34.1 kDa (FCGRT) and 13.1 kDa (B2M) | |
Biotinylated Human FCGRT&B2M; Heterodimer Protein, Avitag,His Tag&Strep; II Tag (SPR and BLI verified) (FCM-H82W4) is expressed from human 293 cells (HEK293). It contains AA Ala 24 - Ser 297 (FCGRT) and Ile 21 - Met 119 (B2M) (Accession # P55899-1 (FCGRT) and P61769-1 (B2M)). | |
-20°C | |
FcRn (FCGRT and B2M) | |
Human | |
PBS, pH7.4 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |