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ACROBiosystems Biotinylated Human CD30 / TNFRSF8 Protein, Avitag™,His Tag

MALS verified

Marke:  ACROBiosystems CD0-H82E6-25UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15826137

  • 403.01 CHF / 25 Mikrogramm


Verfügbar ab
28-05-2021
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Beschreibung

Beschreibung

Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 41.1 kDa. The protein migrates as 60-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_001234.2
HEK293
Human
41.1 kDa
25 µg
Phe 19 - Lys 379
TNFRSF8,CD30,D1S166E,Ki-1
Precision Avi
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>95% as determined by SDS-PAGE
Biotinylated Human CD30, Avitag,His Tag (CD0-H82E6) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2).
-20°C
CD30
His Tag and Avi Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation