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ACROBiosystems Biotinylated Human B7-H7 / HHLA2 Protein, Fc, Avitag™

Biotinylated Protein

Marke:  ACROBiosystems B77-H82F5-200UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15825987

  • 1589.03 CHF / 200 Mikrogramm


Verfügbar ab
28-05-2021
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Beschreibung

Beschreibung

B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 65.9 kDa. The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_009003.1
HEK293
Human
65.9 kDa
200 µg
Ile 23 - Asn 344
B7-H7,HHLA2,B7 Homolog 7
Precision Avi
Tris with Glycine, Arginine and NaCl, pH7.5
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
Powder
>90% as determined by SDS-PAGE
Biotinylated Human B7-H7, Fc,Avitag (B77-H82F5) is expressed from human 293 cells (HEK293). It contains AA Ile 23 - Asn 344 (Accession # Q9UM44-1).
-20°C
B7-H7
Fc Tag and Avi Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation