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Bcl-2 Antibody (8C8), Alexa Fluor™ 700, Novus Biologicals™
Mouse Monoclonal Antibody
Marke: Novus Biologicals NBP2-33313AF700
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Beschreibung
Bcl-2 Monoclonal specifically detects Bcl-2 in Human, Porcine, Primate, Monkey, Mouse (Negative), Rat (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
Spezifikation
| Bcl-2 | |
| Monoclonal | |
| Alexa Fluor 700 | |
| apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2 | |
| Mouse | |
| 25 kDa | |
| 0.1 mL | |
| Apoptosis, Autophagy, Cancer, Cellular Markers, Phospho Specific, Tumor Suppressors | |
| 596 | |
| Human, Pig, Primate, Mouse (Negative), Rat (Negative) | |
| Purified |
| Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen) | |
| 8C8 | |
| Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1-5 μg/mL for coating, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500 | |
| BCL2 | |
| A synthetic peptide, aa41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein. (Uniprot: P10415 ) | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative. | |
| Store at 4C in the dark. | |
| IgG1 κ |
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