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BBS10 Mouse anti-Human, Clone: 4C6A10, Proteintech
Mouse Monoclonal Antibody
Marke: Proteintech 66679-1-IG-150UL
Additional Details : Gewicht : 0.00010kg
Beschreibung
BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein′s expression impairs ciliogenesis in preadipocytes.Spezifikation
BBS10 | |
Monoclonal | |
0.95 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q8TAM1 | |
BBS10 | |
BBS10 Fusion Protein Ag17960 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG2b |
Immunohistochemistry (Paraffin), Western Blot | |
4C6A10 | |
Unconjugated | |
BBS10 | |
Bardet Biedl syndrome 10, BBS10, C12orf58, FLJ23560 | |
Mouse | |
Protein A | |
RUO | |
79738 | |
-20°C | |
Liquid |