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BBS10 Mouse anti-Human, Clone: 4C6A10, Proteintech

Mouse Monoclonal Antibody

Marke:  Proteintech 66679-1-IG-150UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16838785

  • 351.68 CHF / 150 Mikroliter

Verfügbar ab: 28-06-2022
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Beschreibung

Beschreibung

BBS10 is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein′s expression impairs ciliogenesis in preadipocytes.
Spezifikation

Spezifikation

BBS10
Monoclonal
0.95 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q8TAM1
BBS10
BBS10 Fusion Protein Ag17960
150 μL
Primary
Human
Liquid
Immunohistochemistry (Paraffin), Western Blot
4C6A10
Unconjugated
BBS10
Bardet Biedl syndrome 10, BBS10, C12orf58, FLJ23560
Mouse
Protein A
RUO
79738
Antibody
IgG2b
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote