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  6. Invitrogen™ B7-H6 Monoclonal Antibody (JAM1EW), PE, eBioscience™, Invitrogen™

Invitrogen™ B7-H6 Monoclonal Antibody (JAM1EW), PE, eBioscience™, Invitrogen™

Product Code. 16370624
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Menge:
100 Tests
25 Tests
Unit Size:
100 Stück
25 Stück
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16370624 25 Tests 25 Stück
16380624 100 Tests 100 Stück
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Product Code. 16370624 Supplier Invitrogen™ Supplier No. 12652641

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Description

Mouse Monoclonal Antibody

Description: This JAM1EW monoclonal antibody recognizes human B7-H6 (NCR3LG1) protein on the surface of cells. It recognizes protein on live but not on paraformaldehyde-fixed cells. The JAM1EW clone is specific to B7-H6. When tested in flow cytometry against cells transfected with either B7-H4, B7-H5, B7-H6, or B7-H7, clone JAM1EW only stains positively on B7-H6 transfected cells. Applications Reported: This JAM1EW antibody has been reported for use in flow cytometric analysis. Applications Tested: This JAM1EW antibody has been pre-diluted and tested by flow cytometric analysis of HeLa and HL-60 cell line. This may be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser

B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells. B7-H6 binds with NKp30 present on NK cells. Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis. B7-H6 is not constitutively expressed on normal tissue. Whether it can be expressed endogenously under certain conditions is under investigation. B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen B7-H6
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Klon JAM1EW
Konzentration 5 μL/Test
Konjugat PE
Zusammensetzung PBS with BSA and 0.09% sodium azide; pH 7.2
Gen NCR3LG1
Gen-Zugriffsnummer Q68D85
Gen-Alias B7 homolog 6; B7H6; B7-H6; DKFZp686I21167; DKFZp686O24166; natural cytotoxicity triggering receptor 3 ligand 1; natural killer cell cytotoxicity receptor 3 ligand 1; NCR3LG1; putative Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167
Gensymbole NCR3LG1
Wirtsspezies Mouse
Immunogen B7-H6 recombinant protein.
Reinigungsverfahren Affinity chromatography
Menge 25 Tests
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 374383
Zielspezies Human
Inhalt und Lagerung 4°C, store in dark, DO NOT FREEZE!
Produkttyp Antibody
Form Liquid
Isotype IgG1 κ
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