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ARPP-21 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

133.80 CHF - 381.34 CHF

Spezifikation

Antigen ARPP-21
Konzentration 0.38 mg/mL
Anwendungen Immunohistochemistry (Paraffin), Western Blot
Klassifikation Polyclonal
Konjugat Unconjugated
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
16839163
Unterlagen ansehen Aktionsdetails
Proteintech
11829-1-AP-20UL
20 μL
133.80 CHF
20 Mikroliter
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Verfügbar ab: 16-04-2024
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16829163
Unterlagen ansehen Aktionsdetails
Proteintech
11829-1-AP-150UL
150 μL
381.34 CHF
150 Mikroliter
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab: 16-04-2024
Sie sich ein, um den Lagerbestand zu sehen
Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

The autosomal domit cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure′ cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains 41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene.
Spezifikation

Spezifikation

ARPP-21
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rabbit
Human, Mouse, Rat
Q9DCB4, Q9UBL0
10777, 363153, 74100
ARPP-21 Fusion Protein Ag2399
Primary
-20°C
ARPP21
0.38 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
ARPP 21, ARPP21, ARPP-21, RCS, TARPP
Arpp21
IgG
Antigen Affinity Chromatography
Antibody
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Sicherheitsdatenblatt (SDS)
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Dokumentation

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