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Invitrogen™ ARMET Recombinant Rabbit Monoclonal Antibody (012)
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Artikelnummer. 17139015
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Menge:
100 μL
Packungsgröße:
100 Mikroliter
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17139015 100 μL 100 Mikroliter
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Artikelnummer. 17139015 Lieferant Invitrogen™ Lieferanten-Nr. MA529746

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Beschreibung

Rabbit Recombinant Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire. This antibody has specificity for Mouse MANF.

The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen ARMET
Anwendungen ELISA
Klassifikation Recombinant Monoclonal
Klon 012
Konzentration 1 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with no preservative
Gen MANF
Gen-Zugriffsnummer Q9CXI5
Gen-Alias 3230402M22Rik; AA407711; AA408789; AA673178; Arginine-rich protein; arginine-rich, mutated in early stage tumors; ARMET; ARP; D17914; D18Mgi17; Manf; mesencephalic astrocyte derived neurotrophic factor; mesencephalic astrocyte-derived neurotrophic factor; MGC142148; MGC142150; Protein ARMET
Gensymbole MANF
Wirtsspezies Rabbit
Immunogen Recombinant Mouse MANF protein (Met1-Leu179).
Reinigungsverfahren Protein A
Menge 100 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 74840
Zielspezies Mouse
Inhalt und Lagerung Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotype IgG
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