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SMN Mouse, Unlabeled, Clone: 8, BD
Mouse Monoclonal Antibody
270.71 CHF - 496.48 CHF
Spezifikation
| Antigen | SMN |
|---|---|
| Klon | 8 |
| Konzentration | 250μg/mL |
| Anwendungen | Western Blot |
| Klassifikation | Monoclonal |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15875559
|
BD Biosciences
610646 |
50 μg |
 271.00 CHF 270.71 CHF / 1 Set Sparen 0.29 CHF 0.11% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
|
15885559
|
BD Biosciences
610647 |
150 μg |
497.00 CHF 496.48 CHF / 1 Set Sparen 0.52 CHF 0.11% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
Beschreibung
SMN (survival motor neuron) was discovered as a candidate gene, located in chromosome 5q13, for the fatal autosomal Spinal muscular atrophy (SMA) disorder. The SMN gene was missing or interrupted in a significant number of patients with SMA. The SMN protein is 294 amino acids and migrates with apparent molecular weight of 40kDa. In addition to the cytoplasm, other studies localized SMN in dots of 0.1-1.0μm within the nucleus. These novel nuclear structures were named “gems” and found associated to coiled bodies. It was also found that SMN interacts with the RGG box of hnRNP U and fibrillarin. Therefore, the biochemical function of SMN may be in the regulation of mRNA metabolism.
Immunofluorescence, Immunohistochemistry, Western Blotting
Spezifikation
| SMN | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified | |
| Survival Motor Neuron |
| 8 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Canine, Human, Mouse, Rat | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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