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SHP2 Mouse, Unlabeled, Clone: 79, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 610622
Código de producto. 15845549
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495.00 CHF
494.34 CHF / 1 Set
Sparen 0.66 CHF
0.13% Rabatt
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Descripción
SHP2 (also known as PTP1D, Syp, SHPTP2 and PTP2C) is a member of the cytosolic class of protein-tyrosine phosphatases (PTPs). SHP2 has been reported to contain two SH2 domains where both SH2 domains are N-terminal to the PTP catalytic domain. The expression of SHP2 has been reported to be highest in brain, heart, and kidney. The PTPs are thought to function with other protein-tyrosine kinases to maintain intracellular protein phosphotyrosine homeostasis and cell cycle progression. The presence ofSH2 domains in SHP2 (PTP1D) has prompted speculation that binding to specific phosphorylated tyrosine residues is key to its function. SHP2 (PTP1D) is tyrosine- phosphorylated and activated in response to stimulation with EGF or PDGF.
Especificaciones
| SHP2 | |
| Monoclonal | |
| 250μg/mL | |
| PTP1D, Syp, SHPTP2 and PTP2C | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at -20°C. |
| Western Blot | |
| 79 | |
| Unconjugated | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| 150 μg | |
| Cell Biology | |
| Canine, Chicken, Frog, Human, Mouse, Rat | |
| IgG1 |
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