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PRK1 Mouse, Unlabeled, Clone: 49, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 610687

Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15825589

  • 452.00 CHF / 1 Set


Verfügbar ab
08-06-2021
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Beschreibung

Beschreibung

Members of the Protein Kinase C (PKC) family of homologous serine/threonine protein kinases are involved in a number of processes such as cell growth, cell differentiation, and cytokine secretion. PKCs are activated by Ca2+, phospholipids, diacylglycerol, phorbol esters, and proteolysis. PRK1 (PKC-Related Kinase 1, also named PKN) was originally identified in human hippocampus as a novel protein kinase with sequence homology to PKC. PRK1 contains 942 amino acids with an apparent molecular weight of 120kDa. Although activated by limited proteolysis, PRK1 is not activated by Ca2+/diacylglycerol or phorbol esters. However, PRK1 is activated by phospholipids and arachidonic acid. PRK1 may regulate cytoskeletal changes since it binds to Rho-GTP and becomes phosphorylated in vivo, coincidentally with the formation of focal adhesions and stress fibers.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Spezifikation

Spezifikation

PRK1
49
Unconjugated
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Murine
IgG1
RUO
Store undiluted at -20°C.
Monoclonal
Western Blot
250μg/mL
PKN
Affinity Purified
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
150μg
Cell Biology
Primary
Canine, Human, Murine, Rat
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.