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PRK1 Mouse, Unlabeled, Clone: 49, BD
Mouse Monoclonal Antibody
737.00 CHF
Spezifikation
| Antigen | PRK1 |
|---|---|
| Klon | 49 |
| Konzentration | 250μg/mL |
| Anwendungen | Western Blot |
| Klassifikation | Monoclonal |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15825589
|
BD Biosciences
610687 |
150 μg |
Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11. |
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Beschreibung
Members of the Protein Kinase C (PKC) family of homologous serine/threonine protein kinases are involved in a number of processes such as cell growth, cell differentiation, and cytokine secretion. PKCs are activated by Ca2+, phospholipids, diacylglycerol, phorbol esters, and proteolysis. PRK1 (PKC-Related Kinase 1, also named PKN) was originally identified in human hippocampus as a novel protein kinase with sequence homology to PKC. PRK1 contains 942 amino acids with an apparent molecular weight of 120kDa. Although activated by limited proteolysis, PRK1 is not activated by Ca2+/diacylglycerol or phorbol esters. However, PRK1 is activated by phospholipids and arachidonic acid. PRK1 may regulate cytoskeletal changes since it binds to Rho-GTP and becomes phosphorylated in vivo, coincidentally with the formation of focal adhesions and stress fibers.
Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting
Spezifikation
| PRK1 | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified | |
| PKN |
| 49 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Canine, Human, Mouse, Rat | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.