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Phospho-DNA-PK (Thr2647) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Invitrogen PA538475
Additional Details : Gewicht : 0.00900kg
Beschreibung
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.Spezifikation
Phospho-DNA-PK (Thr2647) | |
Polyclonal | |
Unconjugated | |
PRKDC | |
DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350, DNA-PK catalytic subunit, DNA-dependent protein kinase catalytic subunit, hyper-radiosensitivity of murine scid mutation, complementing 1, p460 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
5591 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
1 mg/mL | |
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P78527 | |
PRKDC | |
A synthetic phosphopeptide derived from human DNA-PK around the phosphorylation site of threonine2647 (T-L-TP-Q-T) | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG |