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Nanog Mouse anti-Human, PE, Clone: N31-355, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 560483

Additional Details : Gewicht : 0.02000kg

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Artikelnummer. 15830239

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Beschreibung

Beschreibung

The N31-355 monoclonal antibody reacts with human Nanog (named for Tir Na Nog, the land of the ever-young of Celtic mythology), which is a homeobox transcription factor required for the maintenance of the undifferentiated state of pluripotent stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF (Leukemia Inhibitory Factor) and BMP (Bone Morphogenic Protein). When Nanog expression is down-regulated, cell differentiation can proceed. Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53. Nanog is one of the factors that can contribute to reprogramming of differentiated cells to an induced pluripotent stem cell state.

Host Species: Mouse
Clone: N31-355
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: Human Nanog Recombinant Protein

Intracellular Staining

Spezifikation

Spezifikation

Nanog
N31-355
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG1, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
PE
Affinity Purified
Human Nanog Recombinant Protein
100 Tests
Cell Biology
Primary
Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.