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MEF2D Mouse, Unlabeled, Clone: 9, BD

Mouse Monoclonal Antibody

370.00 CHF - 730.00 CHF

Spezifikation

Antigen MEF2D
Klon 9
Konzentration 250μg/mL
Anwendungen Western Blot
Klassifikation Monoclonal
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15815639
Unterlagen ansehen Aktionsdetails
BD Biosciences
610774
50 μg
370.00 CHF
1 Set
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Verfügbar ab: 22-04-2024
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15825639
Unterlagen ansehen Aktionsdetails
BD Biosciences
610775
150 μg
730.00 CHF
1 Set
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab: 22-04-2024
Sie sich ein, um den Lagerbestand zu sehen
Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

MEF2D is a member of the MEF2 (Myocyte-specific Enhancer-binding Factor 2) transcription factor family. Members of this family (MEF2A, B, C, & D) contain several characteristic motifs that include a MEF2 domain and a MADS box. MEF2 proteins bind the DNA sequence, 5′- (C/T)T(A/T)(A/T)AAATA(A/G)-3′, and binding occurs primarily, although not exclusively, in muscle cells. MEF2D gene expression is ubiquitous and the mRNA is alternatively spliced. This results in multiple protein isoforms that heterodimerize with other family members. In addition to the MEF2 and MADS domains, MEF2D has a glutamine-/proline-rich region, amino acids 365-404, and a basic region, in the MADS domain near the N-terminus. The glutamine-/proline-rich region is involved in transactivation, while the basic region mediates sequence-specific DNA binding. MEF2D displays 75% similarity to hMEF2A and hMEF2C. Myogenin gene transcription requires MEF2D, indicating that MEF2D is involved in myogenesis and muscle cell differentiation. MEF2D has been reported to have a calculated molecular weight of 56kDa, but can be observed migrating in a range of 56-70kDa.

Immunofluorescence, Immunoprecipitation, Western Blotting

Spezifikation

Spezifikation

MEF2D
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
Myocyte-specific Enhancer-binding Factor 2
9
Western Blot
Unconjugated
RUO
Canine, Human, Mouse, Rat
Mouse MEF2D aa. 346-511
Primary
Store undiluted at -20°C.
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Dokumentation

Dokumentation

Product Certifications

For Research Use Only.