IL-2 Rat anti-Mouse, FITC, Clone: JES6-5H4, BD
Rat Monoclonal Antibody
Marke: BD Biosciences 562040
Additional Details : Gewicht : 0.01000kg
The JES6-5H4 monoclonal antibody specifically binds to mouse interleukin-2 (IL-2). IL-2 is a multifunctional cytokine that plays pivotal roles in immunity and tolerance. It is produced by activated T cells. IL-2 effects the activation, growth, proliferation and/or differentiation of various cell types including T and B lymphocytes and their precursors, LAK cells, NK cells, and monocytes/macrophages. IL-2 mediates its biological activities by binding to IL-2 receptor compleses. The intermediate affinity IL-2R is comprised of IL-2R β (CD122) and common gamma chain ( γc; CD132) subunits whereas the high-affinity IL-2R is comprised of IL-2R α (CD25), IL-2R β and γc subunits. The JES6-5H4 monoclonal antibody binds to IL-2 and neutralizes its biological activity.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
|Mouse IL-2 Recombinant Protein|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
For Research Use Only.