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IL-2 Rat anti-Mouse, FITC, Clone: JES6-5H4, BD

Rat Monoclonal Antibody

Marke:  BD Biosciences 562040

Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15831589

  • 127.00 CHF / 1 Stück


Verfügbar ab
08-06-2021
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Beschreibung

Beschreibung

The JES6-5H4 monoclonal antibody specifically binds to mouse interleukin-2 (IL-2). IL-2 is a multifunctional cytokine that plays pivotal roles in immunity and tolerance. It is produced by activated T cells. IL-2 effects the activation, growth, proliferation and/or differentiation of various cell types including T and B lymphocytes and their precursors, LAK cells, NK cells, and monocytes/macrophages. IL-2 mediates its biological activities by binding to IL-2 receptor compleses. The intermediate affinity IL-2R is comprised of IL-2R β (CD122) and common gamma chain ( γc; CD132) subunits whereas the high-affinity IL-2R is comprised of IL-2R α (CD25), IL-2R β and γc subunits. The JES6-5H4 monoclonal antibody binds to IL-2 and neutralizes its biological activity.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Spezifikation

Spezifikation

IL-2
JES6-5H4
FITC
Affinity Purified
Mouse IL-2 Recombinant Protein
25μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.5mg/mL
Aqueous buffered solution containing ≤0.09% sodium azide.
Rat
IgG2b
RUO
Primary
Murine
Videos
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Dokumentation

For Research Use Only.