CD86 Mouse anti-Human, PE, Clone: 2331 (FUN-1), BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 555658
Additional Details : Gewicht : 0.02000kg
2331 (FUN-1) recognizes a 75kDa cell surface protein, CD86 (B70/B7-2), expressed primarily on monocytes and activated B cells. Competitive binding assays demonstrate that, while both 2331 (FUN-1) and IT2.2 (anti-CD86) recognize the same molecule, they react with different epitopes. CD86 is the second ligand for CD28 and CTLA-4 and may play an important role in co-stimulation of T cells in primary immune response. 2331 (FUN-1) blocks costimulation activity of CD86 in functional studies. This antibody is routinely tested on Daudi cells by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Host Species: Mouse
Clone: 2331 (FUN-1)
Isotype: IgG1 κ
Species Reactivity: Human
|B7.2; B7-2; B-lymphocyte activation antigen B7-2; B70; BU63; CD28LG2; LAB72|
|Human HBL-1 Cell Line|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
For Research Use Only.