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CD8 Mouse anti-Human, APC-H7, Clone: SK1, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 560273

Additional Details : Gewicht : 0.00800kg

 Lernen Sie weitere Varianten dieses

Artikelnummer. 15830069

  • 203.00 CHF / 1 Stück


Verfügbar ab
27-05-2021
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Beschreibung

Beschreibung

CD8 recognizes the 32kDa a-subunit of a disulfide-linked bimolecular complex. The majority of peripheral blood CD8+ T lymphocytes express an a/b heterodimer (Mr 32, 30kDa), while CD8+CD16+ natural killer (NK) lymphocytes and CD8+ T-cell receptor (TCR)-γ/δ+ lymphocytes express a/a homodimer (Mr 30kDa). CD8+TCR-α/β+ lymphocytes can express either an α/α homodimer or α/β heterodimer. The CD8 antigenic determinant binds to class I major histocompatibility (MHC) molecules resulting in increased adhesion between the CD8+ T lymphocytes and target cells. Binding of the CD8 antigen is coupled to a protein tyrosine kinase p56lck. The CD8:p56lck complex can play a role in T-lymphocyte activation through mediation of the interactions between the CD8 antigen and the CD3/TCR complex.

Host Species: Mouse
Clone: SK1
Isotype: IgG1 κ
Species Reactivity: Human
Immunogen: Human Peripheral Blood T Cells

Flow Cytometry

Spezifikation

Spezifikation

CD8
SK1
CD8α; CD8A; CD8 alpha; Leu2a; MAL; T8; p32
Affinity Purified
Human Peripheral Blood T Cells
25 Tests
Immunology
Primary
Baboon, Cynomolgus, Human, Rhesus
Flow Cytometry
APC-H7
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
Murine
IgG1, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.