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CD45RO Mouse anti-Human, FITC, Clone: UCHL1, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 561887

Additional Details : Gewicht : 0.02000kg

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Artikelnummer. 15821439

  • 177.00 CHF / 1 Stück


Verfügbar ab
08-06-2021
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

The UCHL1 monoclonal antibody specifically binds to the 180 kDa isoform of CD45 (aka, the Leukocyte Common Antigen). CD45RO is a type I transmembrane glycoprotein that has cytoplasmic protein tyrosine phosphatase activity and functions in signal transduction pathways. This CD45 isoform does not include amino acid sequences encoded by the variable CD45 exons A, B, or C. CD45RO is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a proportion of resting T cells. CD45RO and CD45RA antibodies seem to define complementary, predominantly non-overlapping, populations in resting peripheral T cells, demonstrating heterogeneity within the CD8 and CD4 subpopulations. CD45RO binds to CD22.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Spezifikation

Spezifikation

CD45RO
UCHL1
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG2a, κ
RUO
Primary
Human
Flow Cytometry
FITC
Affinity Purified
Human IL-2-dependent T-cell line
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.