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CD45RO Mouse anti-Human, FITC, Clone: UCHL1, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 561887
Additional Details : Gewicht : 0.02000kg
Beschreibung
The UCHL1 monoclonal antibody specifically binds to the 180 kDa isoform of CD45 (aka, the Leukocyte Common Antigen). CD45RO is a type I transmembrane glycoprotein that has cytoplasmic protein tyrosine phosphatase activity and functions in signal transduction pathways. This CD45 isoform does not include amino acid sequences encoded by the variable CD45 exons A, B, or C. CD45RO is expressed on most thymocytes, activated T cells, memory T cells, granulocytes and monocytes, but only on a proportion of resting T cells. CD45RO and CD45RA antibodies seem to define complementary, predominantly non-overlapping, populations in resting peripheral T cells, demonstrating heterogeneity within the CD8 and CD4 subpopulations. CD45RO binds to CD22.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Spezifikation
| CD45RO | |
| Monoclonal | |
| FITC | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG2a κ |
| Flow Cytometry | |
| UCHL1 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human IL-2-dependent T-cell line | |
| 25 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.