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CD45 Rat anti-Mouse, APC-Cy7, Clone: 30-F11, BD

Rat Monoclonal Antibody

Marke:  BD Biosciences 557659

Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15818978

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Beschreibung

Beschreibung

The 30-F11 clone has been reported to react with all isoforms and both alloantigens of CD45, which is found on hematopoietic stem cells and all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane glycoprotein which is expressed at high levels on the cell-surface, and its presence distinguishes leukocytes from non-hematopoietic cells. CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family, where the intracellular carboxy-terminal region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons 4, 5, and 6 (designated as A, B, and C, respectively). CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction and the CD45 isoforms detected in the mouse are cell type-, maturation-, and activation state-specific.

Spezifikation

Spezifikation

CD45
30-F11
APC-Cyanine7
Aqueous buffered solution containing ≤0.09% sodium azide.
Rat
IgG2b, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
Ptprc; CD45R; LCA; Leukocyte common antigen; T200; B220; Ly-5; Lyt-4
Affinity Purified
Mouse Thymus / Spleen
0.1mg
Immunology
Primary
Murine
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.