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CD40 Mouse anti-Human, APC, Clone: 5C3, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 561848

Additional Details : Gewicht : 0.02000kg

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Artikelnummer. 15831399

  • 209.00 CHF / 1 Stück


Verfügbar ab
03-06-2021
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

This 5C3 monoclonal antibody specifically binds to CD40, a 45-48 kDa type I integral membrane glycoprotein. CD40 is expressed on B lymphocytes, but is not expressed on terminally differentiated B cells. CD40 is also expressed by endothelial cells, basal epithelial cells and some epithelial cell carcinomas, follicular dendritic cells, macrophages, fibroblasts, keratinocytes, and CD34+ hematopoietic progenitor cells. This antibody is useful for studying the roles played by CD40 in B-cell growth, proliferation, and differentiation including immunoglobulin isotype switching. Anti-CD40 antibodies have been reported to stimulate B-cell proliferation when costimulated with anti-µ, anti-CD20 antibodies or with phorbol esters. 5C3 is capable of inducing B-cell proliferation when presented with IL-4.

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Spezifikation

Spezifikation

CD40
5C3
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
APC
Affinity Purified
IgG1, κ
RUO
Primary
Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.