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CD38 Mouse anti-Human, Brilliant Violet 421, Clone: HIT2, BD

Mouse Monoclonal Antibody

352.00 CHF - 785.00 CHF

Spezifikation

Antigen CD38
Klon HIT2
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Konjugat Brilliant Violet 421
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Product Code Brand Menge Price Quantity & Availability  
15831929
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BD Biosciences
562445
25 Tests
352.00 CHF
1 Stück
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Verfügbar ab: 15-05-2024
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15821929
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BD Biosciences
562444
100 Tests
785.00 CHF
1 Stück
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Verfügbar ab: 15-05-2024
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Description

Description

The HIT2 monoclonal antibody specifically binds to CD38. CD38 is a 45 kDa type II single-chain transmembrane glycoprotein present on thymocytes, activated T cells and terminally differentiated B cells (plasma cells). Other reactive cells include monocytes, macrophages, dendritic cells and some epithelial cells. The CD38 antigen acts as an ectoenzyme that catalyzes the synthesis and hydrolysis of a Ca++ mobilizing agent, cyclic ADP-ribose. This intracellular calcium plays an important role in cell signaling pathways. Reports describe CD38 as
participating in adhesion with CD31, immunoregulatory functions involving signal transduction leading to cell growth, apoptosis, and differentiation. The antibody was conjugated to Brilliant Violet 421 and has been developed in collaboration with Sirigen. With an Ex Max of 407-nm and Em Max at 421-nm, Brilliant Violet 421 can be excited by the violet laser and detected in the standard Pacific Blue filter set (eg, 450/50-nm filter). Brilliant Violet 421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Host Species: Mouse
Clone: HIT2
Isotype: IgG1, κ
Species Reactivity: Human

Flow Cytometry

Specifications

Specifications

CD38
Flow Cytometry
Brilliant Violet 421
RUO
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
HIT2
Monoclonal
Mouse
Human
IgG1 κ
Affinity Purified
T10; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1
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