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CD3 Mouse anti-Human, Brilliant Violet 711, Clone: UCHT1, BD

Mouse Monoclonal Antibody

324.00 CHF - 705.00 CHF

Spezifikation

Antigen CD3
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Konjugat Brilliant Violet 711
Wirtsspezies Mouse
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15813039
Unterlagen ansehen Aktionsdetails
BD Biosciences
563724
25 Tests
324.00 CHF
1 Stück
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Verfügbar ab: 23-04-2024
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15823039
Unterlagen ansehen Aktionsdetails
BD Biosciences
563725
100 Tests
705.00 CHF
1 Stück
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab: 23-04-2024
Sie sich ein, um den Lagerbestand zu sehen
Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

The UCHT1 monoclonal antibody specifically binds to the human CD3 ε -chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3 ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3 ε -positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3 ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3 ε .

The antibody was conjugated to BD Horizon™ BV711 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. This dye is a tandem fluorochrome of BD Horizon™ BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 711-nm. BD Horizon™ BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20-nm filter). Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy™5.5 detectors. However, the spillover can be corrected through compensation as with any other dye combination.

Spezifikation

Spezifikation

CD3
Monoclonal
Mouse
Human
IgG1 κ
Affinity Purified
CD3e; CD3E; T3E; TCRE; T-cell surface antigen T3/Leu-4 epsilon
Flow Cytometry
Brilliant Violet 711
RUO
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Product Certifications

For Research Use Only.