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CD3 Mouse anti-Human, BUV395, Clone: UCHT1, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 563548

Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15832879

  • 291.00 CHF / 1 Stück


Verfügbar ab
26-05-2021
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Beschreibung

Beschreibung

The UCHT1 monoclonal antibody specifically binds to the human CD3 ε -chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3 ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3 ε -positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3 ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3 ε .

The antibody was conjugated to BD Horizon™ BUV395 which has been exclusively developed by BD Biosciences as an optimal dye for use on a 355nm laser equipped instrument. With an Ex Max at 348nm and an Em Max at 395nm, this dye has virtually no spillover into any other detector. BD Horizon™ BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.

Spezifikation

Spezifikation

CD3
UCHT1
CD3e; CD3E; T3E; TCRE; T-cell surface antigen T3/Leu-4 epsilon
Affinity Purified
Human infant thymocytes and peripheral blood lymphocytes from a Sezary Syndrome donor
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
Brilliant Ultraviolet 395
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG1, κ
RUO
Primary
Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.