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CD3 Mouse anti-Human, Alexa Fluor 700, Clone: UCHT1, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 557943

Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15819128

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Beschreibung

Beschreibung

The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.

Spezifikation

Spezifikation

CD3
UCHT1
Alexa Fluor 700
Affinity Purified
Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
0.1mg
Immunology
Primary
Human
Flow Cytometry
0.2mg/mL
Aqueous buffered solution containing protein stabilizer and ≤0.09% sodium azide.
Murine
IgG1, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.