CD294 Rat anti-Human, Alexa Fluor 647, Clone: BM16, BD
Rat Monoclonal Antibody
Marke: BD Biosciences 561797
Additional Details : Gewicht : 0.01000kg
The BM16 monoclonal antibody specifically binds to CD294. CD294 is encoded by PTGDR2 (Prostaglandin D2 receptor 2) and is also known as CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), GPR44 (G protein-coupled receptor 44), DL1R, and DP2. CD294 is a member of the G protein-coupled leukocyte chemoattractant receptor family and it is expressed on Th2, but not Th1 type cells. CD294 is detectable on CD4+ T cells in fresh PBMC but not on B cells and NK cells. CD294 is also expressed on peripheral blood basophils and eosinophils, suggesting its involvement allergic reactions. Phenotypic analysis of CD4+ T cells expressing CRTH2 demonstrated that they were also CD45RA-negative and CD45RO+ and CD25+. These cells produce Th2- but little or no Th1-type cytokines upon stimulation with PMA and Ionomycin.
|Alexa Fluor 647|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|CRTH2; PTGDR2 ; Prostaglandin D2 receptor 2; DL1R; DP2; GPR44|
|Human CRTH2 Transfected Cell Line|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
For Research Use Only.