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CD206 Mouse anti-Human, PE-CF594, Clone: 19.2, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 564063

Additional Details : Gewicht : 0.01000kg

Artikelnummer. 15833329

  • 650.00 CHF / 1 Stück
Verfügbar ab: 22-04-2024
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Beschreibung

Beschreibung

The 19.2 monoclonal antibody specifically binds to CD206 which is also known as the macrophage mannose receptor (MMR) or C-type lectin domain family 13 member D (CLEC13D). CD206 is a type I transmembrane glycoprotein of approximately 162 kDa which binds to glycoconjugates containing mannose, fucose, or N-acetylglucosamine. These carbohydrates are present on the surface of many microorganisms and enable the macrophage to bind to microorganisms through the MMR and internalize them during the process of phagocytosis. CD206 is expressed on human macrophages, endothelial cells, and cultured dendritic cells. It is not detected on resting monocytes. Mannose receptor expression is upregulated on peripheral blood mononuclear cells following 3 day incubation with GM-CSF.

This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to PE-Texas Red™. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red™ yet exhibits improved brightness and spectral characteristics. Due to PE having maximal absorption peaks at 496nm and 564nm, PE-CF594 can be excited by the blue (488-nm), green (532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red™ (eg 610/20-nm filter).

Spezifikation

Spezifikation

CD206
Monoclonal
PE-CF594
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human Placental Macrophage Mannose Receptor
100 Tests
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
19.2
Macrophage mannose receptor
Mouse
Affinity Purified
RUO
Human
IgG1 κ
Produktvorschläge

Produktvorschläge

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Dokumentation

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