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CD195 Mouse anti-Human, FITC, Clone: 2D7/CCR5, BD

Mouse Monoclonal Antibody

227.00 CHF - 515.00 CHF

Spezifikation

Antigen CD195
Klon 2D7/CCR5
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Konjugat FITC
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15821299
Unterlagen ansehen Aktionsdetails
BD Biosciences
561747
25 Tests
227.00 CHF
1 Stück
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Verfügbar ab: 22-04-2024
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15818578
Unterlagen ansehen Aktionsdetails
BD Biosciences
555992
100 Tests
515.00 CHF
1 Stück
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab: 22-04-2024
Sie sich ein, um den Lagerbestand zu sehen
Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

Reacts with the chemokine receptor, CCR5, a seven transmembrane-spanning G protein-associated molecule. CCR5 belongs to the β chemokine receptor family. It is expressed on a subset of T lymphocytes (CD3+, CD45RO+, CD95+). CCR5 regulates lymphocyte chemotaxis activation and transendothelial migration during inflammation. It signals a response to at least three chemokines: RANTES and macrophage inflammatory protein-1 (MIP-1) α and β. Additionally, CCR5 has been found to be a co-receptor for macrophage-tropic HIV-1 on CD4+ cells, a characteristic that is important in viral transmission. Reports indicate that individuals who have partial (heterozygous) or complete (homozygous) deletion of the CCR5 allele, demonstrate resistance to HIV infection. This antibody has been shown to block ligand and gp120 binding. It is also able to neutralize HIV infection. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: 2D7/CCR5
Isotype: IgG2a κ
Species Reactivity: Human

Flow Cytometry

Spezifikation

Spezifikation

CD195
Flow Cytometry
FITC
RUO
Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide.
IgG2a κ
Affinity Purified
CCR5; C-C chemokine receptor type 5; CC-CKR-5; CKR5; CHEMR13
2D7/CCR5
Monoclonal
Mouse
Human
Human CCR5 Transfected Cell Line
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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For Research Use Only.