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CD19 Mouse anti-Human, BB515, Clone: HIB19, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 564456

Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15823659

  • 377.00 CHF / 1 Stück


Verfügbar ab
27-05-2021
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

The HIB19 monoclonal antibody specifically binds to the 95 kDa type I transmembrane CD19 glycoprotein. CD19 is expressed during all stages of B-cell maturation and differentiation, except on plasma cells. CD19 is also present on follicular dendritic cells. It is not found on T cells or on normal granulocytes. CD19 is a signal transduction molecule that regulates B cell development, activation, proliferation and differentiation. It associates with the complement receptor 2 (CD21), TAPA-1 (CD81), Leu 13, and/or MHC class II to form a signal transduction complex on the surface of B cells. Anti-CD19 clone HIB19 partially blocks the binding of clone B43, another CD19-specific monoclonal antibody.

The antibody was conjugated to BD Horizon™ BB515 which was developed exclusively by BD Biosciences. With an excitation max of 490nm and an emission max of 515nm, BD Horizon BB515 can be excited by the 488nm laser and detected in a standard FITC set (e.g., 530/30-nm filter). This dye provides a much brighter alternative to FITC with less spillover into the PE detector.

Spezifikation

Spezifikation

CD19
HIB19
B4; B-lymphocyte antigen CD19; Leu-12
Affinity Purified
IgG1, κ
RUO
Primary
Human
Flow Cytometry
BB515
Aqueous buffered solution containing ≤0.09% sodium azide.
Murine
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.