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CD154 Mouse anti-Human, APC, Clone: TRAP1, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 555702

Additional Details : Gewicht : 0.02000kg

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Artikelnummer. 15828378

  • 890.00 CHF / 1 Stück
Verfügbar ab: 23-04-2024
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Beschreibung

Beschreibung

Reacts with CD40 ligand (CD40L), a 39kDa type II membrane glycoprotein expressed on activated T cells. CD40-CD40L interaction plays a very important role in T cell-dependent B-cell proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T cell-B cell interaction affecting subsequent proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T cell-B cell interaction affecting subsequent proliferation, IL-2R expression and differentiation of B cells. In addition, blocking of CD40-CD40L interaction has been demonstrated with soluble CD40, resulting in the inhibition of immunoglobulin isotype switching. It has been reported that patients with X-linked hyper-IgM syndrome have defective expression of functional CD40L due to a defective gene that encodes CD40L. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: TRAP1
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

Spezifikation

Spezifikation

CD154
Monoclonal
APC
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Flow Cytometry
TRAP1
CD40LG; CD40 ligand; CD40L; TNFSF5; T-BAM; TRAP
Mouse
100 Tests
Immunology
Baboon, Cynomolgus, Human, Rhesus Monkey
IgG1 κ
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

For Research Use Only.