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CD154 Mouse anti-Human, APC, Clone: TRAP1, BD

Mouse Monoclonal Antibody

299.00 CHF - 890.00 CHF

Spezifikation

Antigen CD154
Klon TRAP1
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Konjugat APC
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Produkte 2
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Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15880629
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BD Biosciences
560955
25 Tests
299.00 CHF
1 Stück
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Verfügbar ab: 23-04-2024
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15828378
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BD Biosciences
555702
100 Tests
890.00 CHF
1 Stück
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Verfügbar ab: 23-04-2024
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Description

Description

Reacts with CD40 ligand (CD40L), a 39kDa type II membrane glycoprotein expressed on activated T cells. CD40-CD40L interaction plays a very important role in T cell-dependent B-cell proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T cell-B cell interaction affecting subsequent proliferation, differentiation, and memory cell formation. Anti-CD40L mAb partially blocks T cell-B cell interaction affecting subsequent proliferation, IL-2R expression and differentiation of B cells. In addition, blocking of CD40-CD40L interaction has been demonstrated with soluble CD40, resulting in the inhibition of immunoglobulin isotype switching. It has been reported that patients with X-linked hyper-IgM syndrome have defective expression of functional CD40L due to a defective gene that encodes CD40L. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: TRAP1
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

Specifications

Specifications

CD154
Flow Cytometry
APC
RUO
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
TRAP1
Monoclonal
Mouse
Baboon, Cynomolgus, Human, Rhesus Monkey
IgG1 κ
Affinity Purified
CD40LG; CD40 ligand; CD40L; TNFSF5; T-BAM; TRAP
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For Research Use Only.