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CD152 Mouse anti-Human, APC, Clone: BNI3, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 560938

Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15820619

  • 222.00 CHF / 1 Stück


Verfügbar ab
03-06-2021
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Beschreibung

Beschreibung

Reacts with the “cytolytic T lymphocyte-associated antigen”, CTLA-4. CTLA-4 is transiently expressed on activated CD28+ T cells and binds to CD80 and CD86 present on antigen presenting cells (APC) with high avidity. This interaction appears to deliver a negative regulatory signal to the T cell. There are recent reports that indicate that CTLA-4 is also expressed on B cells when cultured with activated T cells, suggesting a possible role of CTLA-4 in the regulation of B-cell response. Immobilized BNI3.1 enhances T-cell proliferation induced by CD3 and CD28. Recent studies have showed that CD152 can be expressed by regulatory T (Treg) cells. It has been found this antibody can stain the
intracellular CD152 on the Treg cells after fixation and permeabilization of cells.

Host Species: Mouse
Clone: BNI3
Isotype: IgG2a κ
Species Reactivity: Human

Flow Cytometry, Intracellular Staining

Spezifikation

Spezifikation

CD152
BNI3
CTLA-4; AILIM; Cytotoxic T-lymphocyte protein 4
Affinity Purified
Human CTLA4 Recombinant Protein
25 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
APC
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG2a, κ
RUO
Primary
Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.