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CD11b/Mac-1 Mouse anti-Human, APC, Clone: ICRF44, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 561015

Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15830689

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Beschreibung

Beschreibung

Reacts with the 165kDa adhesion glycoprotein (Mac-1, integrin αM subunit) which associates with the 95kDa integrin β2 (CD18) to form the CD11b/CD18 complex. CD11b/Mac-1 is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and as a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits PMN aggregation in response to fMLP. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: ICRF44
Isotype: IgG1, κ
Cross Reactivity: Human

Flow Cytometry

Spezifikation

Spezifikation

CD11b
ICRF44
MAC-1A; Mac-1; ITGAM; Integrin alpha M; CR3A; CR-3 alpha; Mo1; SLEB6
Affinity Purified
Human monocytes
25 Tests
Immunology
Primary
Human
Flow Cytometry
APC
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG1, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.