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CD117 Mouse anti-Human, Brilliant Violet 421, Clone: YB5.B8, BD

Mouse Monoclonal Antibody

342.00 CHF - 785.00 CHF

Spezifikation

Antigen CD117
Klon YB5.B8
Anwendungen Flow Cytometry
Klassifikation Monoclonal
Konjugat Brilliant Violet 421
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15831919
Unterlagen ansehen Aktionsdetails
BD Biosciences
562435
25 Tests
342.00 CHF
1 Stück
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Verfügbar ab: 23-04-2024
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15821919
Unterlagen ansehen Aktionsdetails
BD Biosciences
562434
100 Tests
785.00 CHF
1 Stück
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab: 23-04-2024
Sie sich ein, um den Lagerbestand zu sehen
Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

The YB5.B8 monoclonal antibody specifically binds to CD117. CD117, also known as c-Kit, is a 145 kDa cell-surface glycoprotein with tyrosine kinase activity. CD117 is present on hematopoietic progenitor cell subsets, thymocytes, mast cells, hepatocytes and histiocytes.CD117 serves as a cytokine receptor for steel factor (SLF), also known as stem cell factor (SCF) or mast cell growth factor (MGF). The interaction of c-Kit and SLF is crucial to hematopoiesis, mast cell differentiation, melanogenesis, and germ cell development. The ability of
the YB5.B8 antibody to block the binding of c-Kit ligand is still controversial. The antibody was conjugated to Brilliant Violet 421 and has been developed in collaboration with Sirigen. With an Ex Max of 407-nm and Em Max at 421-nm, Brilliant Violet 421 can be excited by the violet laser and detected in the standard Pacific Blue filter set (eg, 450/50-nm filter). Brilliant Violet 421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates.

Host Species: Mouse
Clone: YB5.B8
Isotype: IgG1, κ
Species Reactivity: Human

Flow Cytometry

Spezifikation

Spezifikation

CD117
Flow Cytometry
Brilliant Violet 421
RUO
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
IgG1 κ
Affinity Purified
KIT; c-Kit; SCFR; PBT; Mast/stem cell growth factor receptor
YB5.B8
Monoclonal
Mouse
Human
Acute myelocytic leukemia blasts
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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