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CD106 Rat anti-Mouse, FITC, Clone: 429 (MVCAM.A), BD

Rat Monoclonal Antibody

Marke:  BD Biosciences 553332

Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15817158

  • 378.00 CHF / 1 Stück


Verfügbar ab
01-06-2021
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Beschreibung

Beschreibung

The 429 monoclonal antibody specifically binds to both the long (~110 kDa) transmembrane-spanning form and the truncated (~47 kDa) GPI-linked form of vascular cell adhesion molecule-1 (VCAM-1, CD106). CD106 is constitutively expressed on bone marrow stromal cells, myeloid cells, and splenic dendritic cells. Its expression on endothelial cells is upregulated by inflammatory cytokines and in certain pathologic conditions. CD106 expression has also been detected on apoptotic thymocytes, splenocytes, and lymphoid cell lines. VCAM-1 is a counter-receptor for VLA-4 ( α;4 β; 1 integrin) and LPAM-1 ( α;4 β; 7 integrin), and the 429 antibody partially blocks VCAM-1-mediated binding functions. Source of the immunogen was the mouse preadipose cell line PA6.
Spezifikation

Spezifikation

CD106
429 (MVCAM.A)
FITC
Aqueous buffered solution containing ≤0.09% sodium azide.
Rat
IgG2a, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.5mg/mL
Vcam-1; Vascular cell adhesion molecule 1; Vascular cell adhesion protein 1
Affinity Purified
Mouse preadipose cell line PA6
0.5mg
Immunology
Primary
Murine
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.