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BM28 Mouse, Unlabeled, Clone: 46, BD

Mouse Monoclonal Antibody

370.00 CHF - 610.00 CHF

Spezifikation

Antigen BM28
Klon 46
Konzentration 250μg/mL
Anwendungen Western Blot
Klassifikation Monoclonal
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15815599
Unterlagen ansehen Aktionsdetails
BD Biosciences
610700
50 μg
370.00 CHF
1 Set
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Verfügbar ab: 19-04-2024
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15825599
Unterlagen ansehen Aktionsdetails
BD Biosciences
610701
150 μg
610.00 CHF
1 Set
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab: 16-04-2024
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Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

BM28 is a phosphoprotein that migrates at 125kDa in SDS PAGE with a hyperphosphorylated form migrating as a slightly slower band. The ratio of the phosphorylation states alters with the phases of cell cycle - in M, the “fast” phosphorylated BM28 is the major form found, while in G1 phase, the “slow”, hyperphosphorylated BM28 predominates. The cellular localization of BM28 is also cell cycle dependent. In G1, most of the BM28 is chromatin bound, whereas, by M phase, the BM28 is still nuclear, but not associated with the DNA. BM28 is necessary for both entry into S phase and cell division as determined by microinjection inhibition experiments. Microinjection of a BM28 antibody into synchronised cells in G1 phase inhibits DNA replication. When injected during S phase or later, no effect on DNA replication is seen, but cell division is inhibited.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Spezifikation

Spezifikation

BM28
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgG1
Affinity Purified
46
Western Blot
Unconjugated
RUO
Canine, Chicken, Human, Mouse, Rat
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Store undiluted at -20°C.
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Sicherheitsdatenblatt (SDS)
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For Research Use Only.