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Aluminon, ACS, Thermo Scientific Chemicals

Product Code. 11343298
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Product Code. 11343298 Supplier Thermo Scientific Alfa Aesar Supplier No. 036239.22
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Verfügbar ab: 04-12-2026
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Description

CAS: 569-58-4 | C22H23N3O9 | 473.438 g/mol

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. Its neuroprotective effect, perhaps due to its ability to prevent down-regulation of Ca2+ impermeable GluR2 receptors or to its ability to inhibit calpain, a Ca2+-activated protease that is activated during apoptosis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 569-58-4
Formule moléculaire C22H23N3O9
Poids moléculaire (g/mol) 473.438
Numéro MDL MFCD00040925
Clé InChI AIPNSHNRCQOTRI-UHFFFAOYSA-N
Synonyme aluminon, ammonium aurintricarboxylate, aurintricarboxylic acid ammonium salt, aurintricarboxylic acid, acs
CID PubChem 54729869
ChEBI CHEBI:87398
Nom IUPAC Triazanium ; 5-[(3-carboxy-4-oxydophényl)-(3-carboxy-4-oxycyclohexa-2,5-dien-1-ylidène)méthyl]-2-oxidobenzoate
SMILES C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)[O-])C(=O)[O-])C(=O)O)[O-].[NH4+].[NH4+].[NH4+]

Specifications

Nom chimique ou matériau Aluminon
Point de fusion 220°C to 225°C (decomposition)
pH 5.3
Odeur Odorless
Quantité 100 g
Merck Index 14,322
Informations sur la solubilité Soluble in water(800g/L).
Poids de la formule 473.44
Qualité ACS
Forme physique Poudre

Safety and Handling

compliance-icons
Product Identifier
  • Aluminon, ACS
 Signal Word
  • Attention
 Hazard Category
  • Lésion oculaire grave/irritation oculaire Catégorie 2
  • Corrosion cutanée/irritation cutanée Catégorie 2
 Hazard Statement
  • H315-Provoque une irritation cutanée.
  • H319-Provoque une sévère irritation des yeux.
 Precautionary Statement
  • P280-Porter des gants de protection/des vêtements de protection/un équipement de protection des yeux/ du visage.
  • P302+P352-EN CAS DE CONTACT AVEC LA PEAU: Laver abondamment à l'eau/.
  • P305+P351+P338-EN CAS DE CONTACT AVEC LES YEUX: rincer avec précaution à l'eau pendant plusieurs minutes. Enlever les lentilles de contact si la victime en porte et si elles peuvent être facilement enlevées. Continuer à rincer.
 Supplemental information
  • MIXTURE LIST-Contain: Aluminon
SDS

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