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  5. Invitrogen™ QuantiGene™ Plex Human ADMETOX Panel, 80-plex

Invitrogen™ QuantiGene™ Plex Human ADMETOX Panel, 80-plex

Artikelnummer. 17992001
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Artikelnummer. 17992001 Lieferant Invitrogen™ Lieferanten-Nr. QGP180ADMETOX

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Beschreibung

The QuantiGene Plex Human ADMETOX Panel, 80-plex, enables the measurement of gene expression of all relevant ADME (absorption, distribution, metabolism, and excretion) and toxicological biomarkers through the analysis of 80 RNA targets in a single well using Luminex xMAP technology in combination with branched DNA signal amplification.

The QuantiGene Plex Human ADMETOX Panel, 80-plex, enables the measurement of gene expression of all relevant ADME (absorption, distribution, metabolism, and excretion) and toxicological biomarkers through the analysis of 80 RNA targets in a single well using Luminex xMAP technology in combination with branched DNA signal amplification. Analyze 80 genetic targets implicated in drug metabolism, including enzymes, transporters, and CYPs, as well as toxicology and apoptosis for efficient profiling of your drug discovery and basic research samples.

QuantiGene Plex panels are extensively tested for target combinability, interference, and cross-reactivity to provide the highest level of validation and precision. This kit is not compatible with the MAGPIX instrument.

This panel is used in combination with the QuantiGene Plex Assay Kit (Cat. No. QP1013), which contains all buffers, plates, and detection reagents necessary to perform the assay in 96-well plates. For detailed information, see create custom research panels

  • Rapid turnaround for this catalog panel for fast delivery

    • Targets: ABCA1, ABCB1 , ABCB11, ABCC1, ABCC2, ABCC3 , ABCG2 , ACTB, AOX1, B2M, BAX, BCL2, CASP3,CASP9, CES1, CYP1A1, CYP1A2, CYP2A6, CYP2B6, CYP2C19, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP2J2, CYP3A4, CYP3A5, CYP3A7, DPYD, FMO1, FMO3, FMO5, GAPDH, GSTA2, GSTM1, GSTP1, GSTT1, GUSB, HMGB1, HMGCS2, HNF4A, HPRT1, NAT1, NAT2, PGK1, POLR2A, PPIB, RIPK1, RXRA, SLC10A1, SLC15A1, SLC15A2, SLC16A1, SLC22A1, SLC22A2, SLC22A6, SLC22A7, SLC2A1, SLC3A1, SLCO1B1, SLCO1B3, SLCO2B1, SULT1A1, SULT2A1, SULT2B1, TBP, TFRC, TP53, TPMT, UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A6, UGT1A9, UGT2B15, UGT2B17, UGT2B4, UGT2B7, XDH

    Panel and signal amplification technology

    QuantiGene Plex assays are hybridization-based assays for the direct quantitation of RNA from cell lysates, tissue homogenates, or purified RNA. They enable the measurement of multiple targets in the same well via multiplexing.

    QuantiGene Plex panels contain two components: a target-specific probe set and magnetic capture beads. The target-specific probes are used to capture the RNA of interest, and branched DNA technology then amplifies the fluorescent signals, which are read with a Luminex xMAP instrument. The fluorescent signal is directly proportional to the amount of target mRNA present in the sample. This allows for (relative) quantification of gene expression and with this specific panel enables human immune profiling. Detailed and step-by-step data analysis is facilitated by the Trusted Sustainability Partner
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    Spezifikation

    Format 96-Well
    Zur Verwendung mit (Anwendung) QuantiGene Gene Expression Assay
    Zur Verwendung mit (Geräte) Luminex Instrument
    Inhalt und Lagerung

    Target-specific probe set and magnetic capture beads (premixed and ready to use).

    Store probe set and capture beads at 4°C.

    Do not freeze the capture beads, as they can be damaged if frozen.
    Produktlinie QuantiGene™ Plex
    Produkttyp Multiplex-Panel
    Menge 1 Platte
    Versandbedingung Nasseis
    Probentyp Purified RNA, cell/blood/FFPE lysates, tissue homogenates
    Nachweisverfahren Fluoreszenz
    Research Area Toxicology
    Spezies Human
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    Nur für Forschungszwecke. Nicht zur Verwendung bei diagnostischen Verfahren.

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