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Invitrogen™ Human ACVR1B (ALK4), GST Tag Recombinant Protein
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Menge:
1 mg
10 μg
100 μg
Packungsgröße:
1 Milligramm
10 Mikrogramm
100 Mikrogramm
Beschreibung
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Catalytic.
ACVR1B is a serine/threonine kinase involved in signal transduction and cellular communication. Several truncated ACVR1B isoforms have been reported to be exclusively expressed in human pituitary tumors. Mutations of ACVR1B have been observed in pancreatic adenocarcinomas. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1B encodes activin A type IB receptor, composed of 11 exons. Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants. The mRNA expression of variants 1, 2, and 3 is confirmed, and a potential fourth variant contains an alternative exon 8 and lacks exons 9 through 11, but its mRNA expression has not been confirmed.
Spezifikation
Spezifikation
| Zugriffsnummer | P36896 |
| Konzentration | See Label |
| Zur Verwendung mit (Anwendung) | Kinase Assay |
| Zusammensetzung | 50mM tris HCl with 0.5mM EDTA, 2mM DTT, 150mM NaCl, 50% glycerol, 0.02% Triton X-100 and no preservative; pH 7.5 |
| Gen-ID (Entrez) | 91 |
| Molekulargewicht | 68.2 kDa |
| Name | Human ACVR1B (ALK4), GST Tag |
| pH-Bereich | 7.5 |
| Reinigungsverfahren | Purified |
| Menge | 100 μg |
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